Genetic Inheritance and Alzheimer's Disease
A talk by consultant neurologist Professor Nick Fox on what we have learnt from familial Alzheimer’s disease.
Nick Fox is Professor of Clinical Neurology at the Institute of Neurology, UCL and visiting Professor at the Vrije University Amsterdam. He is Consultant Neurologist to The National Hospital for Neurology and Neurosurgery London. His clinical interests are in young onset and familial dementias. His research has focused on using MRI in Alzheimer’s disease and related disorders to improve diagnosis and to measure progression. He has developed techniques for registration-based atrophy measurements from serial MRI. Using these techniques he has shown that rates of cerebral atrophy predict conversion to AD from mild cognitive impairment and that rates of atrophy correlate with clinical decline. These techniques are now widely used in longitudinal studies and clinical trials in AD and in a number of other neurological conditions.
A particular research focus is familial Alzheimer’s disease, and he helped set up the first familial Alzheimer’s disease support group. He also co-chairs the Alzheimer’s Society’s Research Strategy Council and was a member of the Prime Minister’s Dementia Research Champions Group
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